Hormone replacement therapy (HRT) can lead to moderate weight loss in some people, but results vary widely. The amount of weight lost depends on several factors:
Types of hormones used
- Estrogen
- Progesterone
- Testosterone
- Combination therapies
Doses and delivery methods
- Oral
- Transdermal (patches, gels)
- Injections
- Implants
- Pellets
Individual factors
- Age
- Gender
- Baseline hormone levels
- Diet and exercise habits
- Underlying medical conditions
- Genetics
Weight loss is more likely with:
- Testosterone therapy - May decrease fat mass and increase muscle mass
- Effects seen more in those with low testosterone levels
- Growth hormone - Helps metabolize fat, build muscle
- Only available by prescription
- Appetite suppression - Some hormones curb appetite
- Allows for lower calorie intake
Mechanisms by which hormones affect weight:
- Increase basal metabolic rate - More calories burned at rest
- Burn visceral fat - Around organs; linked to chronic disease
- Build lean muscle mass - Burns more calories than fat
- Regulate distribution of fat and muscle - Changes body composition
- Modulate appetite and cravings - Eat fewer calories
Expected weight loss results:
- 1-10 lbs in first ~3 months
- Ongoing 1-5 lbs per year
Maximal weight loss ~15-30 lbs
Success varies based on:
- Medications used
- Doses
- Changes in diet and exercise
- Underlying medical conditions
- Genetics and hormone sensitivity
| Factor | Effect on Weight Loss |
|-|-|
| Medications | Varies by drug; testosterone has more effect |
| Doses | Higher doses more effective to a point |
| Diet and exercise | Essential for optimal results |
| Medical conditions | Certain illnesses inhibit weight loss |
| Genetics | Great variability in hormone sensitivity |
In summary, ~~
hormone replacement therapy~~ can assist with moderate weight loss of
~15-30 lbs with the right regimen. However, success depends greatly on the individual. Commitment to improved ~~diet~~ and ~~exercise~~ is vital. Those with deficiency symptoms have better outcomes. Genetics play a major role.
Consult a knowledgeable provider to develop realistic expectations. Weight loss is not guaranteed with ~~
hormone therapy~~ but can be helped when properly implemented.
